Can You Take Acetaminophen With Melatonin?

Acetaminophen is both an antipyretic and analgesic medication that cools your body and changes the way you sense pain. Physicians often prescribe acetaminophen to reduce fever associated with colds and flu and to relieve mild to moderate pain from headaches, toothaches, muscle aches, backaches, osteoarthritis and menstrual periods. The medication works by changing the way your body senses pain and cooling down your body. Despite its popular use, acetaminophen is a very dangerous drug that increases your risk of severe liver damage that might not be apparent initially, but can develop into liver failure and cause death within several days.

Melatonin is a hormone that the pineal gland in the brain produces from serotonin, a neurotransmitter, and secretes into the blood at night. The primary function of melatonin is to regulate your circadian rhythm, which influences your wake-sleep cycle. When taken before bedtime, melatonin supplements can induce drowsiness and sleep and improve your overall quality of sleep. Scientists at the Hadassah Medical Center in Jerusalem found that melatonin supplements significantly reduce the amount of time you take to fall asleep, increases the quality of sleep and increases the total amount of time sleeping, according to research published in "Sleep Medicine Reviews" in February 2005.

当合在一起时从来没有因为关于对乙酰氨基酚和褪黑激素之间的不良反应的任何报告为2011年。然而，可能会发生不良反应，和每次服药与副作用相关联。对乙酰氨基酚通常是安全的，当你把它作为指导，但它可引起肝损害，如果你需要超过规定的，哪怕是很小的量。此外，对乙酰氨基酚是在其他缓解疼痛和感冒药的常见成分。褪黑激素是在几个药物类，其中包括抗焦虑，镇静催眠和保健品。美国食品药物管理局报告褪黑激素与某些健康风险，包括小鼠自发性恶性肿瘤的发展，适当的视力丧失，增加斑块在动脉有关。

Just because there is no documentation of an interaction between acetaminophen and melatonin does not mean that an adverse reaction cannot occur. Scientists commonly do not identify adverse interactions between medications and other drugs, nutrients or other substances until long after the FDA approves the medication. Nonetheless, since acetaminophen is associated with serious risks to your liver, it is probably best to take melatonin alone and avoid taking acetaminophen and melatonin together.