Shortness of breath, weight loss, cough and fatigue by themselves are relatively common symptoms in a large variety of medical conditions. When all four are combined, they don't fit in with many different medical medical conditions. If you experience all four of these symptoms together, see your doctor to get an accurate diagnosis as soon as possible. The conditions these symptoms indicate are serious and require prompt treatment.
Lung Cancer
Lung cancer may cause shortness of breath, weight loss, cough and fatigue. Other symptoms may include appetite loss, wheezing, coughing up blood and chest pain. About 20 percent of lung cancers are small cell lung cancers, but the most common type is non-small cell lung cancer, according to PubMed Health. Smoking cigarettes is the leading cause, but other possible causes including high pollution levels, asbestos, radiation therapy to your lungs, arsenic in high levels and radon gas. Type determines treatment; chemotherapy, surgery and radiation are common.
HIV/AIDS
艾滋病病毒是一种传染性疾病，可能最终会导致艾滋病病毒。艾滋病可危及生命和损害你的免疫系统。性交，共用注射器，输血过程中或由母亲传染给孩子，可能会发生艾滋病毒的传播，根据梅奥诊所。开始症状包括头痛，咽痛，发热，皮疹及淋巴结肿大。随着病毒的发展，您可能会遇到腹泻，消瘦，淋巴结肿大，咳嗽，发烧和呼吸困难。一旦这种病毒已经成为艾滋病，症状包括高烧，慢性腹泻，头痛，扭曲或视力模糊，碰伤或皮疹，浸泡盗汗，气短，舌或口腔病变气短，消瘦，咳嗽，寒战和原因不明，持续的体重减轻，根据梅奥诊所。治疗包括药物如非核苷逆转录酶抑制剂，蛋白酶抑制剂，整合酶抑制剂，核苷逆转录酶抑制剂和融合或进入抑制剂。
Pulmonary Tuberculosis
This contagious infection is caused by bacteria and primarily affects your lungs. Symptoms may include cough, excessive sweating, fever, trouble breathing, wheezing, coughing up blood, fatigue, unexplained weight loss and chest pain, according to PubMed Health. Treatment includes drugs, most commonly isoniazid, pyrazinamide, rifampin and ethambutol. To fight the infection, you will most likely receive a combination of drugs.
Diffuse Interstitial Lung Disease
This is a group of disorders affecting the lungs, characterized by inflammation in the deep tissues of the lungs. The primary symptom is shortness of breath. Other symptoms may include dry cough, fatigue, muscle pain, fingernail clubbing, joint pain and bluish lips, nails and skin, according to MedlinePlus. There is no specific treatment, but immunosuppressant drugs and anti-inflammatory drugs may be prescribed.